Science Librarian Claire Curry has created the Data Analytics and Visualization research guide to connect OU library users to local services, data sources, analysis tools, and sources of literature on experimental design, software, and evidence synthesis across many disciplines.
Digital Scholarship and Data Services is a unit that supports OU community members with their data needs. Consult with specialists and graduate assistants who are familiar with working with data, including management, analysis and visualization. With the ability to ask questions and receive guidance, Data Services: Research Data is the focal point to help faculty, researchers, and students work with their data.
The OU Supercomputing Center for Education & Research, a division of OU Information Technology, helps undergraduates, grad students, faculty and staff to learn and use advanced computing in their science and engineering research and education.
EcoCyc is a scientific database for the bacterium Escherichia coli K-12 MG1655. The EcoCyc project performs literature-based curation of the entire genome, and of transcriptional regulation, transporters, and metabolic pathways.
"The Gene Ontology (GO) knowledgebase is the world’s largest source of information on the functions of genes. This knowledge is both human-readable and machine-readable, and is a foundation for computational analysis of large-scale molecular biology and genetics experiments in biomedical research."
The Human Genome Project (HGP) refers to the international 13-year effort, formally begun in October 1990 and completed in 2003, to discover all the estimated 20,000-25,000 human genes and make them accessible for further biological study.
"NEON collects environmental data and archival samples that characterize plant, animals, soil, nutrients, freshwater and atmosphere from 81 field sites strategically located in terrestrial and freshwater ecosystems across the U.S."
AquaDocs is an open access repository covering the natural marine, estuarine/brackish and freshwater environments. It includes all aspects of the science, technology, management and conservation of these environments, their organisms and resources, and the economic, sociological and legal aspects.
The plant collections of the Smithsonian Institution began with the acquisition of specimens collected by the United States Exploring Expedition (1838-1842). These formed the foundation of a National Herbarium which today numbers over 5 million historical plant records, placing it among the world's largest and most important. Over 4.2 million specimen records (including over 115,000 type specimens with images) are currently available in this online catalog
Data Observation Network for Earth (DataONE) is the foundation of new innovative environmental science through a distributed framework and sustainable cyberinfrastructure that meets the needs of science and society for open, persistent, robust, and secure access to well-described and easily discovered Earth observational data.
The NIEHS Environmental Genome Project is a multi-disciplinary, collaborative effort focused on examining the relationships between environmental exposures, inter-individual sequence variation in human genes and disease risk in U.S. populations.
"Qiita (canonically pronounced cheetah) is an entirely open-source microbial study management platform. It allows users to keep track of multiple studies with multiple ‘omics data. Additionally, Qiita is capable of supporting multiple analytical pipelines through a 3rd-party plugin system, allowing the user to have a single entry point for all their analyses. Qiita’s main site provides database and compute resources to the global community, alleviating the technical burdens, such as familiarity with the command line or access to compute power, that are typically limiting for researchers studying microbial ecology. Qiita’s platform allows for quick reanalysis of the datasets that have been deposited using the latests analytical technologies. This means that Qiita’s internal datasets are living data that is periodically re-annotated according to current best practices."
"The regulations of the AWA require that investigators provide Institutional Animal Care and Use Committees (IACUCs) with documentation demonstrating that alternatives to procedures that may cause more than momentary pain or distress to the animals have been considered and that activities do not unnecessarily duplicate previous experiments. A thorough literature search regarding alternatives using relevant sources helps to meet this Federal mandate. "
"Searching for alternatives means considering ways to reduce, refine, or replace whenever there is proposed animal use in research, teaching, or testing. This guide focuses on the Animal Welfare Act (at left, August 1966) and US regulatory compliance in research and education. It is, however, an international concern, and most countries have animal welfare laws and regulations that also require a consideration of alternatives."
"Bibliography on Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing. The National Library of Medicine (NLM) developed ALTBIB to provide access to PubMed citations for users seeking information on alternatives to animal testing. Many citations provide access to free full text."
"Although many of the techniques are relevant to molecular bioinformatics, the motivation for the text is much broader, focusing on topics and techniques that are applicable to a range of scientific endeavors."
The authors "motivate learning with interesting biological and medical examples; they emphasize intuitive understanding; and they focus on real data. The book covers basic topics in introductory statistics, including graphs, confidence intervals, hypothesis testing, comparison of means, regression, and designing experiments." Available on reserves.
"For students or researchers in biology who need to design experiments, sampling programs, or analyze resulting data. [...] The chapters include such topics as linear and logistic regression, simple and complex ANOVA models, log-linear models, and multivariate techniques. The main analyses are illustrated with many examples from published papers and an extensive reference list to both the statistical and biological literature is also included."
"This handbook explains how to establish the framework for an experimental project, how to set up all of the components of an experimental system, design experiments within that system, determine and use the correct set of controls, and formulate models to test the veracity and resiliency of the data." A philosophical guide to experimental design, rather than a statistically focused approach.
"The first part of the book gives a largely non-mathematical introduction to data exploration, univariate methods (including GAM and mixed modelling techniques), multivariate analysis, time series analysis (e.g. common trends) and spatial statistics. The second part provides 17 case studies, mainly written together with biologists who attended courses given by the first authors. [...] The case studies can be used as a template for your own data analysis; just try to find a case study that matches your own ecological questions and data structure, and use this as starting point for you own analysis."
"The Ecological Detective makes liberal use of computer programming for the generation of hypotheses, exploration of data, and the comparison of different models. The authors' attitude is one of exploration, both statistical and graphical."
"The handbook identifies both the advantages of using meta-analysis for research synthesis and the potential pitfalls and limitations of meta-analysis (including when it should not be used). Different approaches to carrying out a meta-analysis are described, and include moment and least-square, maximum likelihood, and Bayesian approaches, all illustrated using worked examples based on real biological datasets."